TB-dx Semi‐Automated Microscopy System for the Diagnosis of Tuberculosis in Peru
BME Department, University of Rochester
Edward Brown III, supervisor; Amy L. Lerner, instructor
PROJECT AIMS: Design of a semiautomated, low cost, microscopy-based tuberculosis diagnostic device to be used in La Hospital Nacionale Del Peru
Throughout the design process, the AD team focused on the development of both hardware and software to mechanically drive the microscope’s stage and the Peruvian students focused on creating image processing code. Together, these systems control the microscope; dynamically capture images of sputum samples, analyze them, and eventually determine a diagnosis via a computer algorithm based on the current Peruvian standard of care.
After extensive collaboration with team members, fellow colleagues, supervisors, and customers, AD has successfully designed and assembled a prototype of the TB‐dx. AD has also incorporated the following needs, outlined by our customers, in our TB‐dx design: a maximum consumer‐end cost of $1,500, a decrease in the amount of time it takes to analyze an individual sample, and an increase in the number of microscope fields of view imaged and processed. We were also asked to design a device that functions within the current Peruvian standard of care. AD has also quantified and evaluated the limitations and constraints introduced with the interactions between the camera, computer, microscope stage, and image processing software.
In addition, AD has submitted the TB‐dx design for consideration in the Mondialogo Engineering Competition. Every year, International groups of engineering students in developing and developed countries involved in design projects that address the eight United Nations Millennium Development Goals are considered for a monetary reward.