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CIsotretinoin (trade name: Accutane) is a powerful drug used in the treatment of acne. Four to five months of Accutane treatment usually leads to relief from acne. It is a powerful drug that is very effective for nearly all types of breakouts. Accutane necessary for moderate to severe acne that failed other treatments. It should be used for severe, scarring acne. Also used for acne present for many years, which do not correspond completely to antibiotic pills and creams. While it has many side effects, in some ways it's safer than long-term use of antibiotics. Most other acne control medication antibiotics that are effective only when used daily. More than two million people have taken this drug, much is known about its safety and effectiveness